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Industrial cytometer


The flow and electrical field within a Horiba Medical cytometer was computed by E. Gibaud (PhD student) in order to illustrate the capabilities of YALES2BIO. This device relies on the Coulter effect to count and assess the volume of the cells present in the diluted blood. The complex geometry of the industrial device is handled thanks to the unstructured mesh used by YALES2BIO while the intense inertial effects due to the particle acceleration at the entrance of the orifice are properly accounted for by solving the Navier-Stokes equations. The movie below illustrates the fact that the cell deformation and associated electrical response (used for both counting and sizing) strongly depend on the trajectory of the cell. A longer movie displaying the global flow organization within the cytometer is available here.

rbc in cytometer
MOVIE: Models of red blood cells flowing in a cytometer and associated electrical pulses.